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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINA5
All Species:
13.03
Human Site:
S374
Identified Species:
35.83
UniProt:
P05154
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05154
NP_000615
406
45702
S374
G
T
I
F
T
F
R
S
A
R
L
N
S
Q
R
Chimpanzee
Pan troglodytes
XP_001153393
423
47849
S384
A
V
R
I
T
L
L
S
A
L
V
E
T
R
T
Rhesus Macaque
Macaca mulatta
NP_001038198
231
25839
A219
E
S
G
T
R
A
A
A
A
T
G
Q
S
S
C
Dog
Lupus familis
XP_537545
407
45804
S373
E
A
I
F
M
F
K
S
A
P
M
R
P
H
K
Cat
Felis silvestris
Mouse
Mus musculus
P70458
405
45603
S372
G
A
I
F
T
F
R
S
A
R
P
S
S
L
K
Rat
Rattus norvegicus
P09006
418
46633
S382
G
V
K
F
V
P
M
S
A
K
L
D
P
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516508
456
51272
S417
G
I
K
I
M
Y
K
S
A
P
F
I
P
P
L
Chicken
Gallus gallus
XP_421344
437
49694
S401
G
T
E
F
A
P
H
S
V
P
P
V
I
K
F
Frog
Xenopus laevis
NP_001081358
433
48891
M399
A
F
E
I
M
P
M
M
L
P
P
N
I
Q
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
52.7
72.7
N.A.
64.2
45.9
N.A.
43.6
43
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.8
55.1
84.7
N.A.
80.5
61.2
N.A.
62.5
63.3
58.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
13.3
33.3
N.A.
66.6
33.3
N.A.
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
26.6
53.3
N.A.
80
46.6
N.A.
33.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
23
0
0
12
12
12
12
78
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
23
0
23
0
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
12
0
56
0
34
0
0
0
0
12
0
0
0
12
% F
% Gly:
56
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% H
% Ile:
0
12
34
34
0
0
0
0
0
0
0
12
23
0
12
% I
% Lys:
0
0
23
0
0
0
23
0
0
12
0
0
0
12
23
% K
% Leu:
0
0
0
0
0
12
12
0
12
12
23
0
0
23
12
% L
% Met:
0
0
0
0
34
0
23
12
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% N
% Pro:
0
0
0
0
0
34
0
0
0
45
34
0
34
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
23
0
% Q
% Arg:
0
0
12
0
12
0
23
0
0
23
0
12
0
12
12
% R
% Ser:
0
12
0
0
0
0
0
78
0
0
0
12
34
12
0
% S
% Thr:
0
23
0
12
34
0
0
0
0
12
0
0
12
0
12
% T
% Val:
0
23
0
0
12
0
0
0
12
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _